Role of carnitine in disease Nutrition & Metabolism Springer Nature Link Fatty acid transport into mitochondria by carnitine transporter Role of L carnitine in the transportation of long chain fatty acid across the mitochondria membrane. Short Note On Carnitine Shuttle: Fatty acids are oxidized in mitochondria, and synthesized in the cytoplasm. Long chain fatty acids must form an active intermediate, fatty acyl CoA, before being oxidized inside mitochondria. Catherine